able optical
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1988) have
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applied in
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] by Pilgrim
994, 1995).
ion between
ninimise the
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an may be
ind corneal
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opriate than
le methods
he utility of
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st fit radius
e of corneal
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ower and to
er of points
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ute reliably
a over any
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itely than it
e accuracy
. Keratocon
rithms used
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y addressed
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94).
6. CONCLUSIONS
An accurate knowledge of the topography of the anterior
surface of the human cornea is essential in a wide range of
ophthalmic applications. None of the commercially available
methods of measuring corneal topography provide an
accurate topographic map of the entire cornea, particularly
when the cornea is diseased or scarred.
A photogrammetric method of measuring corneal topography
has been developed. The method does not rely on corneal
reflectance and no assumptions need to be made about the
approximate or specific geometry of the cornea. Using non-
metric cameras, an accuracy of +20um has been obtained.
The instrument has provided complete and accurate
measurements of corneas not well suited to current
commercially available corneal mapping systems, particularly
grafted and keratoconic corneas.
Full automation of image matching is likely to be the greatest
problem to be overcome in a digital implementation of the
Keratocon. The task is to obtain sufficient contrast between
the targets and the pupil, iris and sclera to allow
segmentation of the targets from the background. Additional
experimentation with a teflon membrane appears to be the
most likely route to a reliable solution.
The ophthalmic market place has demonstrated that many
clinicians will be satisfied with an instrument that only maps
corneas that have relatively small departures from normality.
Given these conditions, and the fact that a photogrammetric
instrument is unlikely to be less expensive than a
videokeratoscope, it appears unlikely that a digital
implementation of the Keratocon is commercially viable if its
only advantage is that it provides higher three dimensional
accuracy because of its rigorous photogrammetric solution.
The key to producing a commercially viable instrument is
incorporating into the instrument's software the capacity to
apply the three dimensional data to high quality data analysis
and visualisation. Existing corneal mapping systems still
provide only crude visualisation and analysis tools. A digital
Keratocon should provide sophisticated visualisation of
corneal topography, be able to derive parameters such as
corneal power, and have surface matching capability.
Medical photogrammetry, if it is to be of use to the
practitioner, must extend beyond the task of measurement
alone. Spatial measurement in isolation is generally of
limited value. The task is more likely to be an analysis of
temporal change, long term in the case of progressive
disease, short term in the case of motion analysis; or a
measurement that must be linked to function, such as the
functional link between corneal topography and refractive
power.
449
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